Scientists have long seen parallels between healing wounds and growing tumors. In studying the molecular changes that occur within both, a research team has discovered a new cancer-fuelling mechanism that potentially could inform drug development.

The centromere region of chromosomes retains the same DNA from one generation to the next. Scientists have gained new insights into how it avoids being scrambled in normal cells, and how it becomes unstable in cancer.

There are more than 25 drugs to control HIV, yet the virus remains one of the world’s biggest health problems. One of the many challenges with existing therapies is that a dormant version of the virus is always lurking in the background, ready to attack the immune system as soon as treatment is i...

New findings from Rockefeller University researchers could guide the development of potent combination therapies that deliver more effective and durable treatment of leukemia. In recent work published in Nature, they show it’s possible to deactivate cellular programs involved in tumor growth by d...

A new biologic agent—the most potent of its kind so far—is showing early promise as part of a potential new strategy for treating HIV. The drug, known as 10-1074, may also offer a new way to prevent viral infection in people who are at high risk to acquire HIV, the virus that causes AIDS. ...

Without antiretroviral drug treatment, the majority of people infected with HIV ultimately develop AIDS, as the virus changes and evolves beyond the body’s ability to control it. But a small group of infected individuals—called elite controllers—possess immune systems capable of defeating the ...

Elaine Fuchs, Rebecca C. Lancefield Professor and head of the Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, has been honored with the 2017 McEwen Award for Innovation. The prize, given by the International Society for Stem Cell Research, recognizes groundbreaking wo...

As early humans shed the hairy coats of their closest evolutionary ancestors, they also gained a distinct feature that would prove critical to their success: a type of sweat gland that allows the body to cool down quickly. Those tiny glands are enormously useful, allowing us to live in a wide var...

byĚýAlexandra MacWade, assistant editor A new $10 million endowment gift made by the Donald A. Pels Charitable Trust will provide ongoing support for the university’s chemical and structural biologists through the Pels Family Center for Biochemistry and Structural Biology. Mr. Pels, who was a Roc...

Elaine Fuchs, Rebecca C. Lancefield Professor and head of the Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, has won the 2016 Vanderbilt Prize in Biomedical Science for her innovative use of reverse genetics to understand skin diseases and cancer stem cells. The priz...