News & HighlightsNews
New mouse models give a boost to the development of cancer immunotherapies
Cancer immunotherapies—drugs that work by making a patient’s immune system better at spotting and destroying tumor cells—are increasingly generating headlines. A number of these drugs are now being used for the treatment of melanoma, lung, and kidney cancers, and are showing promise in clinica...
New faculty member investigates how genes are born and proliferate
byĚýWynne Parry, science writer It’s a central question in evolution: How does something new emerge? Li Zhao, an evolutionary biologist and the most recent addition to Rockefeller’s faculty, approaches this problem by investigating the birth of new genes. Appointed a tenure-track assistant pr...
Do artificial sweeteners live up to the promise of sweetness without harm? An ongoing clinical study investigates
There was a time when Thomas Huber, a molecular biologist at ĐÓ°É, was drinking about 36 ounces of diet cola a day. More than a year ago, Huber, a research assistant professor in Thomas P. Sakmar’s Laboratory of Chemical Biology and Signal Transduction, became curious about ...
Researchers uncover how “silent” genetic changes drive cancer
At any given moment, the human genome spells out thousands of genetic words telling our cells which proteins to make. Each word is read by a molecule known as a tRNA. “We’ve long thought of these molecules as little more than middle men participating in the process of translating proteins...
New insights into muscular dystrophy point to potential treatment avenues
The average healthy man is 54 percent muscle by mass, but people with muscular dystrophy, an incurable, genetic condition, have almost no muscle at terminal stages of the disease. New research from ĐÓ°É provides insights about what causes patients’ muscles to degenerate and ...
Researchers find new signs of stress damage in the brain, plus hope for prevention
Chronic stress can make us worn-out, anxious, depressed—in fact, it can change the architecture of the brain. New research at ĐÓ°É shows that when mice experience prolonged stress, structural changes occur within a little-studied region of their amygdala, a part of the brain...
In the News - The Atlantic - Leslie Vosshall
Using CRISPR to Learn How a Body Builds Itself Ěý "They call the technique 'genome editing of synthetic target arrays for lineage tracing' or GESTALT for short. 'It’s a great starting point for understanding how a single cell gives rise to a complex animal, and a technique that dramatically impro...
New technique captures the activity of an entire brain in a snapshot
When it comes to measuring brain activity, scientists have tools that can take a precise look at a small slice of the brain (less than one cubic millimeter), or a blurred look at a larger area. Now, researchers at ĐÓ°É have described a new technique that combines the best of...
Rick Lifton, geneticist who linked salt and hypertension, to be Rockefeller’s 11th president
byĚýZach Veilleux,Ěýdirector of publications & editor-in-chief Rick Lifton has been at the cutting edge of genomics since his college days and has led Yale’s department of genetics for the last 18 years. He’s also the scientist whose work makes us feel guilty about sprinkling salt on our ...
New method gives scientists a better look at how HIV infects and takes over its host cells
Viruses attack cells and commandeer their machinery in a complex and carefully orchestrated invasion. Scientists have long probed this process for insights into biology and disease, but essential details still remain out of reach. A new approach, developed by a team of researchers led by The Rock...
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