News & HighlightsNews
BMP protein maintains crosstalk between cells that control hair growth
Genes, it turns out, are only as active as the signals that turn them on and off. Now scientists from Rockefeller University have identified the signaling molecule that ratchets up and clamps down the activity of key genes in dermal papilla, a type of skin cell whose unique collection of proteins...
Experimental HIV vaccine gets a boost from '70s-era discovery
Although science is known for being a forward-looking field, researchers have found that they can often benefit from a glance over their shoulders. By combining an experimental AIDS vaccine with a long-neglected molecule called poly-IC, Rockefeller University scientists discovered that they were ...
For treating advanced Parkinson's, new research points to serotonin
For most people with Parkinson’s disease, the only relief from the tremors, rigidity and impaired movement associated with the progressive loss of their motor skills is a drug called L-DOPA. But as the disease progresses, L-DOPA can cause prominent side effects that counteract its effectiveness. ...
Structural study of anthrax yields new antibiotic target
Researchers studying anthrax knew they were onto something when they discovered an opponent the bacterium couldn’t outwit. Probing a bit deeper, they discovered this was because the attacker was interacting with something anthrax requires to survive: a carbohydrate in its cell wall. Now, in a stu...
Protein that controls hair growth also keeps stem cells slumbering
Like fine china and crystal, which tend to be used sparingly, stem cells divide infrequently. It was thought they did so to protect themselves from unnecessary wear and tear. But now new research from Rockefeller University has unveiled the protein that puts the brakes on stem cell division and s...
Protein discovered that prevents HIV from spreading
In a study that could open up the field of virology to an entirely new suite of possibilities and that paves the way for future drug research, scientists at Rockefeller University and the Aaron Diamond AIDS Research Center have pinned down a molecule on the surface of human cells that helps keep ...
Mammalian protein plays unexpected role in cell division, and perhaps cancer
The French Nobel laureate Jacques Monod famously said, “What’s true forĚýE.coliĚýis true for an elephant.” With this in mind, researchers at Rockefeller University set out to determine the function of Tel2, a protein originally found in yeast where it maintains the length of chromosome tips ca...
New model of a nuclear pore complex is based on crystal structure of its key component
Everything that goes in and out of a cell’s nucleus must pass through one of its nuclear pores. In the second nuclear pore study to come out of Rockefeller University in as many months, researchers have determined the crystal structure of one of the pore’s main components and used it to propose ...
Altering the balance of immune-cell receptors could help treat cancer and autoimmune diseases
Dendritic cells are responsible for directing the body’s immune response, and they’re activated through receptors on their surfaces. Now, in research that may have implications for novel disease therapies, Rockefeller University scientists have shown that the balance of two different versions of...
Two forces of arousal converge on the "satiety center" of the brain
By pitting two forces — hunger and circadian rhythms — against each other, researchers at Rockefeller University have identified the region of the brain that first registers changes in food availability. The research, in mice, suggests that shifting the timing of a meal increases mental alertnes...
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