News & HighlightsNews
Researchers unveil new monkey model for HIV
By altering just one gene in HIV-1, scientists have succeeded in infecting pig-tailed macaque monkeys with a human version of the virus that has until now been impossible to study directly in animals. The new strain of HIV has already been used to demonstrate one method for preventing infection a...
New protein identified in bacterial arsenal
Nearly a billion years ago, bacteria evolved an insidious means of infecting their hosts — a syringe-like mechanism able to inject cells with stealthy hijacker molecules. These molecules, called virulence factors, play a sophisticated game of mimicry, imitating many of the cells’ normal activiti...
Bacteria-killing enzyme cures mice with fatal pneumonia
Before the advent of antibiotics, pneumonia claimed so many lives — and was so feared — that it was called the “captain of the ship of death.” Now, at a time when the new antibiotics have proved futile against resistant strains of bacteria, researchers at Rockefeller University are using aĚý...
Brain encodes complex plumes of odors with a simple code
In the real world, odors don’t happen one puff at a time. Animals move through, and subsequently distort, plumes of odor molecules that constantly drift, changing direction as the wind disperses them. Now, by exploring how animals smell odors under naturalistic conditions, Rockefeller University ...
Protein found linking stress and depression
Stress, the ever-present threat to health and happy living, is tough on the brain. If the strain goes on too long, it can lead to debilitating psychological problems. Part of the reason, according to scientists at ĐÓ°É, may have to do with a little-known family of proteins c...
Brain protein may be a target for fast-acting antidepressants
It takes weeks or months for the effect of most antidepressants to kick in, time that can feel like an eternity to those who need the drugs the most. But new research suggests that a protein called p11, previously shown to play a role in a person’s susceptibility to depression, activates a seroto...
Gene linked to anxious behavior in mice
To measure anxiety in a mouse and suggest it’s similar to anxiety in a person may seem like a stretch, but the metrics sound uncannily familiar. Paralyzed by fear, afraid to leave the house or socialize with others, scared of new places, preferring the dark to the light of day. Researchers at The...
Dendritic cells as a new player in arteries and heart valves
In 1973,ĚýRalph M. SteinmanĚýlaunched a new scientific discipline when he published his discovery of the dendritic cell, an odd-shaped player in the immune system. Since then, dendritic cells have proved to be critical sentinels on the lookout for foreign invaders, involved in early immune response...
Molecular machine turns packaged messenger RNA into a linear transcript
For RNA, the gateway to a productive life outside the nucleus is the nuclear pore complex, an amalgamation of 30 kinds of proteins that regulates all traffic passing through the nuclear membrane. New research from Rockefeller University shows that one of these proteins magnetically couples with a...
Stem cells in hair follicles point to general model of organ regeneration
Most people consider hair as a purely cosmetic part of their lives. To others, it may help uncover one of nature’s best-kept secrets: the body’s ability to regenerate organs. Now, new research from Rockefeller University gets to the root of the problem, revealing that a structure at the base of ...
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