News & HighlightsNews
Sweat glands grown from newly identified stem cells
To date, few fundamentals have been known about the most common gland in the body, the sweat glands that are essential to controlling body temperature, allowing humans to live in the world’s diverse climates. Now, in a tour de force, researchers at ĐÓ°É and the Howard Hughes...
Rockefeller scientists pioneer new method to determine mechanisms of drug action
Knowing that a drug works is great. Knowing how it works is a luxury. And until now, determining a drug’s mechanism of action has been a tedious and difficult process for scientists. Researchers led by Tarun Kapoor at ĐÓ°É, in collaboration with Olivier Elemento at Weill Cor...
Influenza “histone mimic” suppresses antiviral response
For a virus like influenza, the key to success isn’t in overpowering the immune system, it’s in tricking it. A team of researchers led by scientists at ĐÓ°É has identified a novel mechanism by which influenza viruses hijack key regulators of the human body’s normal antivi...
Study in fruit flies reveals a gene affecting the ability to sleep
On the surface, it’s simple: when night falls, our bodies get sleepy. But behind the scenes, a series of complex molecular events, controlled by our genes, is hard at work to make us groggy. Now, research suggests that a newly identified gene known as insomniacĚýmay play a role in keeping us aslee...
In cancer, molecular signals that recruit blood vessels also trigger metastasis
Cancer cells are most deadly when they’re on the move — able not only to destroy whatever organ they are first formed in, but also to create colonies elsewhere in the body. New research has now shown how a small RNA prevents the recruitment and formation of blood vessels near cancer cell destine...
Resident protection
First "live" imaging of specialized immune system cells reveals new clues about body’s security system To keep the body safe, the immune system enlists more than one form of protection. A circulating task force of immune system cells monitors the body’s periphery, and sends information back to ...
Statin-intolerant patients need a different type of clinical trial, Rockefeller researchers say
Millions of people take statins, the blockbuster drug that lowers low-density lipoprotein (LDL), the so-called bad cholesterol. But as many as 20 percent of them develop adverse effects such as muscle fatigue and weakness and impaired cognition. Rockefeller University scientists Patricia Maningat...
DNA testing by high school students shows many teas contain unlisted ingredients
Your tea may not be what you think. Three New York City high school students, working with Rockefeller scientists, have found several herbal brews and a few brands of tea contain ingredients unlisted on the manufacturers’ package. The teen sleuths also demonstrated new-to-science genetic variatio...
Scientists identify broad and potent HIV antibodies that mimic CD4 binding
In a finding that may be good news for scientists developing HIV vaccines and therapies, a team of researchers at ĐÓ°É and the Howard Hughes Medical Institute have found a way to investigate the broadly neutralizing antibody response against the CD4 binding site of HIV on a ...
Cancer stem cells identified, offering new drug targets
Like carpet bombing, traditional chemotherapy is not very discriminating. Both can cause disastrous collateral damage and still fail to take out the real enemy. New research offers the potential for a surgical strike against cancer that would target only its root cause — cancer stem cells. Elaine...
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