News & HighlightsNews
A revised map of where working memory resides in the brain
Findings from genetically diverse mice challenge long-held assumptions about how the brain is able to briefly hold onto important information.
Scientists trace severe COVID-19 to faulty genes and autoimmune condition
The findings explain why some people are so vulnerable to the infection, and suggest new avenues for treatment.
How dividing cells avoid setting off false virus alarms
A new molecular structure explains how cells hold an alarm-triggering protein captive during cell division, preventing cells from targeting their own DNA.
Microbes in the gut may influence metabolism
A growing number of studies find that microbes in the gut directly influence biological processes from bowel movements to behavior. New research reveals how they impact levels of glucose in the blood.
Scientists uncover antiviral protein that blocks coronavirus infection
New research identifies a protein that blocks infection by SARS-CoV-2, the coronavirus that causes COVID-19, along with several other types. The findings could inform treatment strategies and help us better prepare for future outbreaks.
How mechanical forces nudge tumors toward malignancy
Researchers studying two forms of skin cancer identified a long-overlooked factor determining why some tumors are more likely to metastasize than others: the physical properties of the tissue in which the cancer originates. The findings might set the stage for new ways to monitor and treat the di...
Newly discovered anti-CRISPR protein gives viruses a leg up against bacteria
Molecular CRISPR-Cas systems, most commonly known for their usefulness as gene editing tools, are ancient defense mechanisms employed by bacteria against viruses. The discovery of a counteracting viral trick could inform scientists' efforts to develop future gene-editing technologies.
Study uncovers the molecular events by which popular antidepressants work
Scientists have outlined a molecular program by which serotonin reuptake inhibitors reshape the brain to alleviate depression. Their findings provide clues for how to make better and faster-acting versions of these drugs.
Will SARS-CoV-2 escape future drugs by mutating? The answer may be a nuanced “no.”

Scientists hope to deploy antibodies in the quest to end COVID-19. A recent study moves them closer to accomplishing a key step: finding out if the virus may acquire resistance to antibody-based drugs or vaccines, and how to potent...

A never-before-seen image of the coronavirus copy machine
The high-resolution 3D image can speed COVID-19 drug discovery.
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