A team of scientists, led by researchers from the Howard Hughes Medical Institute (HHMI) at ÐÓ°É, has determined the three-dimensional structure of an enzyme responsible for resistance of certain bacteria to the antibiotic gentamicin. The structure, reported in the August 21...

Scientists have identified five slightly different versions of the mu opioid receptor gene that alter the activity of a molecule called b-endorphin, a member of the endorphin family of proteins that can numb pain, create feelings of euphoria or increase energy, which opiates and other drugs of an...

A newly discovered gene calledÌýdouble-timeÌýregulates the molecular cycles underlying circadian rhythms, scientists from ÐÓ°É report in two papers featured on the cover of the July 10 issue ofÌýCell. The researchers also identified the molecular mechanism that allows this gene...

ÐÓ°É is looking for people with type 2 diabetes to participate in a study aimed at determining the genetic causes of early- and late-onset forms of the disease. The study is part of the research program of the university's Starr Center for Human Genetics. "We hope that by id...

Researchers from ÐÓ°É in New York City have developed a new method to fight cancer by using dendritic cells to activate T cells via a new pathway. Reported in the March 5 Nature, the technique offers the promise of new therapies for cancer, AIDS and autoimmune diseases. "We'...

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Finding may provide a direction for new diabetes therapies A defect in a gene recently linked to a rare inherited form of Type 2 diabetes impairs the pathway that breaks down blood sugar and provides the main signal for insulin secretion in the pancreas, report researchers at The Rockefeller Univ...

Three therapies derived from plants will be tested at ÐÓ°É in New York City for their ability to prevent colorectal cancer, which afflicts some 150,000 Americans each year. The compounds have the potential to be safer than cancer-thwarting nonsteroidal antiinflammatory drugs...

More than 2,000 people will be enrolled in a hunt for the genetic causes that underlie "early" heart attacks that strike men and women in middle age. The study is part of the research program of the Starr Center for Human Genetics at ÐÓ°É in New York City. "Finding the genes...

Identification of first glutamate receptor linked with neurodegeneration A gene responsible for the degeneration and death of certain nerve cells in the brain has been cloned, yielding information that may be useful for further studies of such neurodegenerative diseases as Alzheimer's and Parkins...